A RARE CASE OF LATE-DIAGNOSED GIANT PRIMARY MULTIPLE ANGIOMA OF THE SMALL INTESTINE MESENTERY AND LIVER
Abstract
Background. Angiomas are benign neoplasms made up of blood and lymphatic vessels and are found in various organs. Lymphangiomas of the abdominal cavity most often occur in the mesentery of the small intestine and are more common in children. Large mesenteric lymphangiomas in adults are a very rare pathology. Objective. To present a rare case of late diagnosed giant cavernous cystic lymphangioma of the mesentery of the small intestine alongside with hepatic hemangioma in an elderly woman who did not seek medical care for a long time. Material and methods. The clinical manifestations, laboratory and instrumental findings, as well as autopsy of a patient died due to viral-bacterial pneumonia (SARS-CoV-2 + bacterial infection, unspecified) were analyzed. During the examination of the patient, a large abdominal tumor of unclear genesis and unspecified origin was detected. After the autopsy, a pathohistological examination of the detected neoplasms of the mesentery of the small intestine and liver was performed, which made it possible to establish the diagnosis. Results. As a result of the autopsy, it was established that the patient, in addition to viral-bacterial pneumonia, had a giant cavernous cystic lymphangioma of the small intestine alongside with a hemangioma of the liver. The mass of the mesenteric tumor was 9350 g, the tumor size was 32.5 × 35.0 × 28.0 cm. The size of the hemangioma of the right liver lobe was 5 × 4 × 4 cm. Conclusion. Tumor progression, increased intra-abdominal pressure, compression of abdominal organs, high diaphragm position, as well as other factors contributed to the development and severe course of viral-bacterial pneumonia. The immediate cause of death was intoxication and progressive pulmonary-cardiac insufficiency.
References
Altyev BK, Mirzakulov AG, Madiev RZ, Vervekina TA, Khakimov AT. Limfangioma bryzhejki tonkoj kishki [Lymphangioma of mesentery]. Vestnik jekstrennoj mediciny [The Bulletin of Emergency Medicine]. 2017;1:69-72. (Russian).
Gromov AI, Gorinov AV, Galljamov EA. Limfangioma bryzhejki kishki s hileznym soderzhimym. Osobennosti otobrazhenija na protivofaznyh MR-posledovatelnostjah [Мesenteric chillous lymphangioma. visualization features on opposed-phase MR images]. Medicinskaja vizualizacija [Medical visualization]. 2019;23(4):86-92. https://doi.org/10.24835/1607-0763-2019-4-86-92. https://www.elibrary.ru/ucrgcc. (Russian).
Stoyko YuM, Levchuk AL, Shimkovich SS. Hirurgicheskoe lechenie pacienta s gigantskoj zabrjushinnoj mikrokistiznoj limfangiomoj bryzhejki tonkoj kishki [Surgical Treatment of Patients With Giant Retroperitoneal Microcystins Lymphangiomas of the Mesentery]. Vestnik Nacionalnogo mediko-hirurgicheskogo Centra im. N.I. Pirogova [Bulletin of Pirogov National Medical & Surgical Center]. 2019;14(2):132-133. https://doi.org/10.25881/BPNMSC.2019.99.86.028. https://www.elibrary.ru/dumozj. (Russian).
Sharoev TA, Burkov IV, Kovalev DV, Klimchuk OV, Bondarenko SB, Illarionov YuV. Limfangiomy bryzhejki tonkoj kishki u detej (obzor literatury i sobstvennye klinicheskie nabljudenija) [Lymphangioma of mesentery in children (Iiterature review and own clinical supervision)]. Rossijskij vestnik detskoj hirurgii anesteziologii i reanimatologii [Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care]. 2012;2(2):58-63. edn: PAOTPB. (Russian).
Karaseva OV, Kapustin VA, Agayanc AO, Gorelik AL, Kislyakov AN. Limfangioma kak prichina zavorota podvzdoshnoj kishki [Lymphangioma as a cause of ileus]. Detskaja hirurgija [Russian Journal of Pediatric Surgery]. 2019;23(2):91-94. https://doi.org/10.18821/1560-9510-2019-23-2-91-94. https://www.elibrary.ru/lbvtoo. (Russian).
Buccoliero AM, Castiglione F, Maio V, Morelli C, Martin A, Messineo A, Taddei GL. Calcified cystic lymphangioma of the mesentery: case report. Fetal Pediatr Pathol. 2009;28(5):209-215. https://doi.org/10.3109/15513810903073203.
Siddique K, Bhandari S, Basu S. Giant mesenteric lymphangioma: a rare cause of a life-threatening complication in an adult. BMJ Case Rep. 2010;2010:bcr0420102896. https://doi.org/10.1136/bcr.04.2010.2896.
Dayan D, Raz M, Kuriansky J. Giant Cavernous Hemangioma of Small Intestine Mesentery: A Rare Cause of Recurrent Acute Symptomatic Anemia. Isr Med Assoc J. 2019;21(6):424-425.
Grodek L, Korczyńska-Tartanus B, Bielecki K, Zmora J, Malinowska M, Dmoch-Gajzlerska E. Cystic lymphangioma arising from the small intestine mesentery incidentally found during surgery for a large ovarian tumor – a case report. Wiad Lek. 2022;75(9):2170-2173. https://doi.org/10.36740/WLek202209122.